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Factor XI Anion-Binding Sites are required for Productive Interactions with Polyphosphate
BACKGROUND: Conversion of factor XI (FXI) to factor XIa (FXIa) is enhanced by polymers of inorganic phosphate (polyP). This process requires FXI to bind to polyP. Each FXIa subunit contains anion-binding sites (ABSs) on the apple 3 (A3) and catalytic domains that are required for normal heparin-medi...
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| Glavni autori: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3865764/ https://ncbi.nlm.nih.gov/pubmed/24118982 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.12414 |
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