Mice Lacking NCF1 Exhibit Reduced Growth of Implanted Melanoma and Carcinoma Tumors

The NADPH oxidase 2 (NOX2) complex is a professional producer of reactive oxygen species (ROS) and is mainly expressed in phagocytes. While the activity of the NOX2 complex is essential for immunity against pathogens and protection against autoimmunity, its role in the development of malignant tumor...

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Detalhes bibliográficos
Main Authors: Kelkka, Tiina, Pizzolla, Angela, Laurila, Juha Petteri, Friman, Tomas, Gustafsson, Renata, Källberg, Eva, Olsson, Olof, Leanderson, Tomas, Rubin, Kristofer, Salmi, Marko, Jalkanen, Sirpa, Holmdahl, Rikard
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3865299/
https://ncbi.nlm.nih.gov/pubmed/24358335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084148
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