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Overexpression of E2F3 promotes proliferation of functional human β cells without induction of apoptosis

The mechanisms that control proliferation, or lack thereof, in adult human β cells are poorly understood. Controlled induction of proliferation could dramatically expand the clinical application of islet cell transplantation and represents an important component of regenerative approaches to a funct...

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Detalhes bibliográficos
Main Authors: Rady, Brian, Chen, Yanmei, Vaca, Pilar, Wang, Qian, Wang, Yong, Salmon, Patrick, Oberholzer, José
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3865059/
https://ncbi.nlm.nih.gov/pubmed/23907129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.25834
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