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TOSO promotes β-cell proliferation and protects from apoptosis
Decreased β-cell mass reflects a shift from quiescence/proliferation into apoptosis, it plays a crucial role in the pathophysiology of diabetes. A major attempt to restore β-cell mass and normoglycemia is to improve β-cell survival. Here we show that switching off the Fas pathway using Fas apoptotic...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3757648/ https://ncbi.nlm.nih.gov/pubmed/24024120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2012.08.006 |
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