Recruitment into stress granules prevents irreversible aggregation of FUS protein mislocalized to the cytoplasm

Eitemau Tebyg

• Multistep process of FUS aggregation in the cell cytoplasm involves RNA-dependent and RNA-independent mechanisms
  gan: Shelkovnikova, Tatyana A., et al.
  Cyhoeddwyd: (2014)
• Frameshift peptides alter the properties of truncated FUS proteins in ALS-FUS
  gan: An, Haiyan, et al.
  Cyhoeddwyd: (2020)
• RNA-binding ability of FUS regulates neurodegeneration, cytoplasmic mislocalization and incorporation into stress granules associated with FUS carrying ALS-linked mutations
  gan: Daigle, J. Gavin, et al.
  Cyhoeddwyd: (2013)
• Entorhinal cortical neurons are the primary targets of FUS mislocalization and ubiquitin aggregation in FUS transgenic rats
  gan: Huang, Cao, et al.
  Cyhoeddwyd: (2012)
• Early lethality and neuronal proteinopathy in mice expressing cytoplasm-targeted FUS that lacks the RNA recognition motif
  gan: ROBINSON, HANNAH K., et al.
  Cyhoeddwyd: (2015)