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Global structures of IgG isotypes expressing identical variable regions

Until relatively recently the immunoglobulin molecule was viewed as composed of two independent domains comprised of the variable (V) and constant (C) regions. However, recent work has established that the C region mediates allosteric changes in the V region that can influence specificity and affini...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Eryilmaz, Ertan, Janda, Alena, Kim, Jungwook, Cordero, Radames J.B., Cowburn, David, Casadevall, Arturo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3864969/
https://ncbi.nlm.nih.gov/pubmed/23911417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2013.06.006
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