Mechanism of farnesylated CAAX protein processing by the integral membrane protease Rce1

CAAX proteins play essential roles in multiple signalling pathways, controlling processes such as proliferation, differentiation and carcinogenesis (1). The ~120 mammalian CAAX proteins function at cellular membranes and include the Ras superfamily of small GTPases, nuclear lamins, the γ-subunit of...

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Hauptverfasser: Manolaridis, Ioannis, Kulkarni, Kiran, Dodd, Roger B., Ogasawara, Satoshi, Zhang, Ziguo, Bineva, Ganka, Reilly, Nicola O’, Hanrahan, Sarah J., Thompson, Andrew J., Cronin, Nora, Iwata, So, Barford, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3864837/
https://ncbi.nlm.nih.gov/pubmed/24291792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12754
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