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Small-Molecule Inhibitors of the Rce1p CaaX Protease
The Rce1p protease is required for the maturation of the Ras GTPase and certain other isoprenylated proteins and is considered a chemotherapeutic target. To identify new small-molecule inhibitors of Rce1p, the authors screened the National Cancer Institute Diversity Set compound library using in vit...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2007
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2173876/ https://ncbi.nlm.nih.gov/pubmed/17942791 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057107307226 |
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