Absence of the CAAX Endoprotease Rce1: Effects on Cell Growth and Transformation

After isoprenylation, the Ras proteins and other CAAX proteins undergo two additional enzymatic modifications—endoproteolytic release of the last three amino acids of the protein by the protease Rce1 and methylation of the carboxyl-terminal isoprenylcysteine by the methyltransferase Icmt. This posti...

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Detalhes bibliográficos
Main Authors: Bergo, Martin O., Ambroziak, Patricia, Gregory, Cria, George, Amanda, Otto, James C., Kim, Edward, Nagase, Hiroki, Casey, Patrick J., Balmain, Allan, Young, Stephen G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC134215/
https://ncbi.nlm.nih.gov/pubmed/11739732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.1.171-181.2002
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