Deficient eNOS phosphorylation is a mechanism for diabetic vascular dysfunction contributing to increased stroke size

BACKGROUND AND PURPOSE: Phosphorylation of eNOS, an important post-translational modulator of its enzymatic activity, is reduced in diabetes. We hypothesized that modulation of eNOS phosphorylation could overcome diabetic vascular dysfunction and improves the outcome to stroke. METHODS: We used the...

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Autores principales: Li, Qian, Atochin, Dmitriy, Kashiwagi, Satoshi, Earle, John, Wang, Annie, Mandeville, Emiri, Hayakawa, Kazuhide, d'Uscio, Livius V., Lo, Eng H., Katusic, Zvonimir, Sessa, William, Huang, Paul
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3864831/
https://ncbi.nlm.nih.gov/pubmed/23988642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.113.002073
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