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A Simple, Scalable Synthetic Route to (+)- and (−)-Pseudoephenamine

[Image: see text] A three-step synthesis of pseudoephenamine suitable for preparing multigram amounts of both enantiomers of the auxiliary from the inexpensive starting material benzil is described. The sequence involves synthesis of the crystalline mono-methylimine derivative of benzil, reduction o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mellem, Kevin T., Myers, Andrew G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3864801/
https://ncbi.nlm.nih.gov/pubmed/24138164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol402815d
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