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A Simple, Scalable Synthetic Route to (+)- and (−)-Pseudoephenamine

[Image: see text] A three-step synthesis of pseudoephenamine suitable for preparing multigram amounts of both enantiomers of the auxiliary from the inexpensive starting material benzil is described. The sequence involves synthesis of the crystalline mono-methylimine derivative of benzil, reduction o...

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Detalhes bibliográficos
Main Authors: Mellem, Kevin T., Myers, Andrew G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3864801/
https://ncbi.nlm.nih.gov/pubmed/24138164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol402815d
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