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A Simple, Scalable Synthetic Route to (+)- and (−)-Pseudoephenamine

[Image: see text] A three-step synthesis of pseudoephenamine suitable for preparing multigram amounts of both enantiomers of the auxiliary from the inexpensive starting material benzil is described. The sequence involves synthesis of the crystalline mono-methylimine derivative of benzil, reduction o...

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Autors principals: Mellem, Kevin T., Myers, Andrew G.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3864801/
https://ncbi.nlm.nih.gov/pubmed/24138164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol402815d
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