Enzyme-mediated spatial segregation on individual polymeric support beads: application to generation and screening of encoded combinatorial libraries.

Proteolysis of short N alpha-protected peptide substrates bound to polyoxyethylene-polystyrene beads releases selectively free amino sites in the enzyme-accessible "surface" area. The substantial majority of functional sites in the "interior" of the polymeric support are not reac...

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Hauptverfasser: Vágner, J, Barany, G, Lam, K S, Krchnák, V, Sepetov, N F, Ostrem, J A, Strop, P, Lebl, M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1996
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC38645/
https://ncbi.nlm.nih.gov/pubmed/8710846
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