Metabolism of 17-Alpha-Hydroxyprogesterone Caproate by Human Placental Mitochondria

Perfusion of 17-alpha-hydroxyprogesterone caproate (17HPC) via the maternal circuit of a dually perfused human placental lobule resulted in the extensive formation of 2 metabolites. On the other hand, human placental microsomes biotransformed 17HPC into 5 monohydroxylated metabolites, which did not...

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Bibliographic Details
Main Authors: Fokina, Valentina M., Zharikova, Olga L., Hankins, Gary D. V., Ahmed, Mahmoud S., Nanovskaya, Tatiana N.
Format: Artigo
Language:Inglês
Published: SAGE Publications 2012
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3864459/
https://ncbi.nlm.nih.gov/pubmed/22138546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1933719111419248
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