Malaria life cycle intensifies both natural selection and random genetic drift

Analysis of genome sequences of 159 isolates of Plasmodium falciparum from Senegal yields an extraordinarily high proportion (26.85%) of protein-coding genes with the ratio of nonsynonymous to synonymous polymorphism greater than one. This proportion is much greater than observed in other organisms....

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Bibliografiske detaljer
Main Authors: Chang, Hsiao-Han, Moss, Eli L., Park, Daniel J., Ndiaye, Daouda, Mboup, Souleymane, Volkman, Sarah K., Sabeti, Pardis C., Wirth, Dyann F., Neafsey, Daniel E., Hartl, Daniel L.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2013
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3864301/
https://ncbi.nlm.nih.gov/pubmed/24259712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1319857110
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