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Phosphorylation of the Rab exchange factor Sec2p directs a switch in regulatory binding partners

Sec2p is a guanine nucleotide exchange factor that promotes exocytosis by activating the Rab GTPase Sec4p. Sec2p is highly phosphorylated, and we have explored the role of phosphorylation in the regulation of its function. We have identified three phosphosites and demonstrate that phosphorylation re...

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Bibliographic Details
Main Authors: Stalder, Danièle, Mizuno-Yamasaki, Emi, Ghassemian, Majid, Novick, Peter J.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3864272/
https://ncbi.nlm.nih.gov/pubmed/24248333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1320029110
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