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Phosphorylation of the Rab exchange factor Sec2p directs a switch in regulatory binding partners

Sec2p is a guanine nucleotide exchange factor that promotes exocytosis by activating the Rab GTPase Sec4p. Sec2p is highly phosphorylated, and we have explored the role of phosphorylation in the regulation of its function. We have identified three phosphosites and demonstrate that phosphorylation re...

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Autores principales: Stalder, Danièle, Mizuno-Yamasaki, Emi, Ghassemian, Majid, Novick, Peter J.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3864272/
https://ncbi.nlm.nih.gov/pubmed/24248333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1320029110
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