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Oncogene abnormalities in a series of primary melanomas of the sinonasal tract: NRAS mutations and cyclin D1 amplification are more frequent than KIT or BRAF mutations
Primary malignant melanoma of sinonasal tract (PMMST) is a rare but severe form of melanoma. We retrospectively analyzed 17 cases and focused on the histological presentation, the expression of c-Kit, EGFR, cyclin-D1/Bcl-1, PS100 and HMB45 and searched for BRAF, NRAS and KIT mutations that are known...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
W B Saunders
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3864067/ https://ncbi.nlm.nih.gov/pubmed/23664541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.humpath.2013.01.025 |
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