The Prognostic Value of BRAF, C-KIT, and NRAS Mutations in Melanoma Patients With Brain Metastases

PURPOSE: Brain metastases are a common problem in patients with melanoma, but little is known about the effect of gene mutations on survival in these patients. METHODS AND MATERIALS: We created a retrospective multi-institutional database of 823 patients with melanoma and brain metastases diagnosed...

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Publicado en:Int J Radiat Oncol Biol Phys
Autores principales: Sperduto, Paul W., Jiang, Wen, Brown, Paul D., Braunstein, Steve, Sneed, Penny, Wattson, Daniel A., Shih, Helen A., Bangdiwala, Ananta, Shanley, Ryan, Lockney, Natalie A., Beal, Kathryn, Lou, Emil, Amatruda, Thomas, Sperduto, William A., Kirkpatrick, John P., Yeh, Norman, Gaspar, Laurie E., Molitoris, Jason K., Masucci, Laura, Roberge, David, Yu, James, Chiang, Veronica, Mehta, Minesh
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6925531/
https://ncbi.nlm.nih.gov/pubmed/28721890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2017.03.030
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