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Importance of the loop at residues 230-245 in the allosteric interactions of Escherichia coli aspartate carbamoyltransferase.

Site-directed mutagenesis has been used to replace tyrosine-240 with phenylalanine in each of the catalytic chains of aspartate carbamoyltransferase. Tyrosine-240 is part of a loop in the structure of the enzyme, between residues 230 and 245, which undergoes a substantial conformation change as the...

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Detaylı Bibliyografya
Asıl Yazarlar: Middleton, S A, Kantrowitz, E R
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1986
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC386397/
https://ncbi.nlm.nih.gov/pubmed/3526342
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