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The pAR5 mutation and the allosteric mechanism of Escherichia coli aspartate carbamoyltransferase.

Mutation pAR5 replaces residues 145'-153' at the C terminus of the regulatory (r) chains of Escherichia coli ATCase by a new sequence of six residues. The mutated enzyme has been shown to lack substrate cooperativity and inhibition by CTP. Solution X-ray scattering curves demonstrate that,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cherfils, J, Vachette, P, Tauc, P, Janin, J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1987
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC553711/
https://ncbi.nlm.nih.gov/pubmed/3315652
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