RNA splicing and intron turnover are greatly diminished by a mutant yeast branch point.
Two mutant genes, both of which contain an A----C transversion at the absolutely conserved branch point of the yeast "TACTAAC box" (TACTAAC----TACTACC), were constructed and introduced into yeast cells. Splicing and gene expression are almost completely eliminated by this mutation, but a low level (...
Enregistré dans:
| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1986
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386390/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3090547/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.16.5835 |
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