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RNA splicing and intron turnover are greatly diminished by a mutant yeast branch point.

Two mutant genes, both of which contain an A----C transversion at the absolutely conserved branch point of the yeast "TACTAAC box" (TACTAAC----TACTACC), were constructed and introduced into yeast cells. Splicing and gene expression are almost completely eliminated by this mutation, but a low level (...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Jacquier, A, Rosbash, M
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1986
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386390/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3090547/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.16.5835
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