Down-regulation of OPA1 alters mouse mitochondrial morphology, PTP function, and cardiac adaptation to pressure overload

AIMS: The optic atrophy 1 (OPA1) protein is an essential protein involved in the fusion of the mitochondrial inner membrane. Despite its high level of expression, the role of OPA1 in the heart is largely unknown. We investigated the role of this protein in Opa1(+/−) mice, having a 50% reduction in O...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Piquereau, Jerome, Caffin, Fanny, Novotova, Marta, Prola, Alexandre, Garnier, Anne, Mateo, Philippe, Fortin, Dominique, Huynh, Le Ha, Nicolas, Valérie, Alavi, Marcel V., Brenner, Catherine, Ventura-Clapier, Renée, Veksler, Vladimir, Joubert, Frédéric
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2012
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3863708/
https://ncbi.nlm.nih.gov/pubmed/22406748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvs117
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