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The Immunoproteasome as a Target in Hematologic Malignancies
Suppression of proteasome function with the first-in-class small molecule inhibitor bortezomib is a rational therapeutic strategy against several hematologic malignancies, including multiple myeloma and mantle cell lymphoma. Second generation inhibitors such as carfilzomib, ixazomib, and marizomib t...
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| Huvudupphovsmän: | , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2012
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3863635/ https://ncbi.nlm.nih.gov/pubmed/22726549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.seminhematol.2012.04.003 |
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