Involvement of Asn-293 in stereospecific agonist recognition and in activation of the beta 2-adrenergic receptor.

To investigate the molecular mechanism for stereospecific binding of agonists to beta 2-adrenergic receptors we used receptor models to identify potential binding sites for the beta-OH-group of the ligand, which defines the chiral center. Ser-165, located in transmembrane helix IV, and Asn-293, situ...

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Detaylı Bibliyografya
Asıl Yazarlar: Wieland, K, Zuurmond, H M, Krasel, C, Ijzerman, A P, Lohse, M J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1996
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC38632/
https://ncbi.nlm.nih.gov/pubmed/8799191
Etiketler: Etiketle
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