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BCCIP is required for the nuclear localization of the p21 protein

The p21 (CDKN1A, Waf1 or Cip1) protein is widely known as an inhibitor of cyclin-dependent kinase (CDK), which plays a critical role in regulation of the G(1)-S transition during the cell cycle progression. The inhibition of G(1)-S transition by p21 is mainly mediated in the nucleus. However, the cy...

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Autori principali: Fan, Jinjiang, Wray, Justin, Meng, Xiangbing, Shen, Zhiyuan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3862257/
https://ncbi.nlm.nih.gov/pubmed/19713748
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