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Requirement of Bccip for the Regeneration of Intestinal Progenitors
BCCIP was originally identified as a BRCA2 and CDKN1A/p21 interaction protein. Although a partial loss of BCCIP function is sufficient to trigger genomic instability and tumorigenesis, complete deletion of BCCIP is lethal to cells. Using Rosa26-CreERT2 mouse models, we found that induced Bccip delet...
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| Publicado no: | Am J Pathol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Investigative Pathology
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7857062/ https://ncbi.nlm.nih.gov/pubmed/33039352 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2020.09.009 |
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