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BCCIP Suppresses Tumor Initiation but is Required for Tumor Progression

Dysfunctions of genome caretaker genes contribute to genomic instability and tumor initiation. Because many of the caretaker genes are also essential for cell viability, permanent loss of function of these genes would prohibit further tumor progression. How essential caretaker genes contribute to tu...

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Bibliographic Details
Main Authors: Huang, Yi-Yuan, Dai, Li, Gaines, Dakim, Droz-Rosario, Roberto, Lu, Huimei, Liu, Jingmei, Shen, Zhiyuan
Format: Artigo
Language:Inglês
Published: 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918420/
https://ncbi.nlm.nih.gov/pubmed/24145349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-1766
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