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Tumor derived TGF-Beta mediates conversion of CD4+Foxp3+ regulatory T cells in a murine model of pancreas cancer
CD4(+)25(+)Foxp3(+) regulatory T cells (Treg) play a critical role in the induction of tolerance to tumor associated antigens and suppression of anti-tumor immunity. How Treg are induced in cancer is poorly understood. We reported previously that Treg are significantly elevated in the peripheral blo...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3862184/ https://ncbi.nlm.nih.gov/pubmed/19307989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e318189f13c |
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