Whole-genome sequencing to establish relapse or re-infection with Mycobacterium tuberculosis: a retrospective observational study

BACKGROUND: Recurrence of tuberculosis after treatment makes management difficult and is a key factor for determining treatment efficacy. Two processes can cause recurrence: relapse of the primary infection or re-infection with an exogenous strain. Although re-infection can and does occur, its impor...

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Autori principali: Bryant, Josephine M, Harris, Simon R, Parkhill, Julian, Dawson, Rodney, Diacon, Andreas H, van Helden, Paul, Pym, Alex, Mahayiddin, Aziah A, Chuchottaworn, Charoen, Sanne, Ian M, Louw, Cheryl, Boeree, Martin J, Hoelscher, Michael, McHugh, Timothy D, Bateson, Anna L C, Hunt, Robert D, Mwaigwisya, Solomon, Wright, Laura, Gillespie, Stephen H, Bentley, Stephen D
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2013
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3861685/
https://ncbi.nlm.nih.gov/pubmed/24461758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S2213-2600(13)70231-5
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