Direct Comparison of Xpert MTB/RIF Assay with Liquid and Solid Mycobacterial Culture for Quantification of Early Bactericidal Activity

The early bactericidal activity of antituberculosis agents is usually determined by measuring the reduction of the sputum mycobacterial load over time on solid agar medium or in liquid culture. This study investigated the value of a quantitative PCR assay for early bactericidal activity determinatio...

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Autors principals: Kayigire, Xavier A., Friedrich, Sven O., Venter, Amour, Dawson, Rodney, Gillespie, Stephen H., Boeree, Martin J., Heinrich, Norbert, Hoelscher, Michael, Diacon, Andreas H.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
Matèries:
Mycobacteriology and Aerobic Actinomycetes
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716052/
https://ncbi.nlm.nih.gov/pubmed/23596237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.03290-12
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