Evolution of Drug Resistance in Mycobacterium tuberculosis: Clinical and Molecular Perspective

Por Gillespie, Stephen H.
Publicado em 2002

Improved power for TB Phase IIa trials using a model-based pharmacokinetic–pharmacodynamic approach compared with commonly used analysis methods

Por Svensson, Robin J., Gillespie, Stephen H., Simonsson, Ulrika S. H.
Publicado no J Antimicrob Chemother (2017)

A spatially heterogeneous network-based metapopulation software model applied to the simulation of a pulmonary tuberculosis infection

Por Pitcher, Michael J., Bowness, Ruth, Dobson, Simon, Gillespie, Stephen H.
Publicado no Appl Netw Sci (2018)

OMNIgene.SPUTUM suppresses contaminants while maintaining Mycobacterium tuberculosis viability and obviates cold-chain transport

Por Azam, Khalide, Cadir, Nureisha, Madeira, Carla, Gillespie, Stephen H., Sabiiti, Wilber
Publicado no ERJ Open Res (2018)

Modelling the effects of bacterial cell state and spatial location on tuberculosis treatment: Insights from a hybrid multiscale cellular automaton model

Por Bowness, Ruth, Chaplain, Mark A.J., Powathil, Gibin G., Gillespie, Stephen H.
Publicado no J Theor Biol (2018)

Heat Inactivation Renders Sputum Safe and Preserves Mycobacterium tuberculosis RNA for Downstream Molecular Tests

Por Sabiiti, Wilber, Azam, Khalide, Esmeraldo, Ezembro, Bhatt, Nilesh, Rachow, Andrea, Gillespie, Stephen H.
Publicado no J Clin Microbiol (2019)

A Practical Guide to Measuring Mutation Rates in Antibiotic Resistance

Por Pope, Cassie F., O'Sullivan, Denise M., McHugh, Timothy D., Gillespie, Stephen H.
Publicado em 2008

A Practical Guide to Measuring Mutation Rates in Antibiotic Resistance

Por Pope, Cassie F., O'Sullivan, Denise M., McHugh, Timothy D., Gillespie, Stephen H.
Publicado em 2009

Novel PCR-Restriction Fragment Length Polymorphism Method for Determining Serotypes or Serogroups of Streptococcus pneumoniae Isolates

Por Batt, Sarah L., Charalambous, Bambos M., McHugh, Timothy D., Martin, Siobhan, Gillespie, Stephen H.
Publicado em 2005

Rifampicin Resistance in Tuberculosis Outbreak, London, England

Por Jenkins, Claire, Claxton, Alleyna P., Shorten, Robert J., McHugh, Timothy D., Gillespie, Stephen H.
Publicado em 2005

Moxifloxacin Replacement in Contemporary Tuberculosis Drug Regimens Is Ineffective against Persistent Mycobacterium tuberculosis in the Cornell Mouse Model

Por Liu, Yingjun, Pertinez, Henry, Davies, Geraint R., Gillespie, Stephen H., Coates, Anthony R., Hu, Yanmin
Publicado no Antimicrob Agents Chemother (2018)

Molecular Bacterial Load Assay Concurs with Culture on NaOH-Induced Loss of Mycobacterium tuberculosis Viability

Por Mtafya, Bariki, Sabiiti, Wilber, Sabi, Issa, John, Joseph, Sichone, Emanuel, Ntinginya, Nyanda E., Gillespie, Stephen H.
Publicado no J Clin Microbiol (2019)

Sequetyping: Serotyping Streptococcus pneumoniae by a Single PCR Sequencing Strategy

Por Leung, Marcus H., Bryson, Kevin, Freystatter, Kathrin, Pichon, Bruno, Edwards, Giles, Charalambous, Bambos M., Gillespie, Stephen H.
Publicado em 2012

Comparison of Variable Number Tandem Repeat and IS6110-Restriction Fragment Length Polymorphism Analyses for Discrimination of High- and Low-Copy-Number IS6110 Mycobacterium tuberc...

Por Barlow, Rachael E. L., Gascoyne-Binzi, Deborah M., Gillespie, Stephen H., Dickens, Anne, Qamer, Shabnam, Hawkey, Peter M.
Publicado em 2001

Streptococcus pseudopneumoniae Identification by Pherotype: a Method To Assist Understanding of a Potentially Emerging or Overlooked Pathogen

Por Leung, Marcus H., Ling, Clare L., Ciesielczuk, Holly, Lockwood, Julianne, Thurston, Sarah, Charalambous, Bambos M., Gillespie, Stephen H.
Publicado em 2012

Label-free optical vibrational spectroscopy to detect the metabolic state of M. tuberculosis cells at the site of disease

Por Baron, Vincent O., Chen, Mingzhou, Clark, Simon O., Williams, Ann, Hammond, Robert J. H., Dholakia, Kishan, Gillespie, Stephen H.
Publicado no Sci Rep (2017)

A Population Pharmacokinetic Model Incorporating Saturable Pharmacokinetics and Autoinduction for High Rifampicin Doses

Por Svensson, Robin J., Aarnoutse, Rob E., Diacon, Andreas H., Dawson, Rodney, Gillespie, Stephen H., Boeree, Martin J., Simonsson, Ulrika S.H.
Publicado no Clin Pharmacol Ther (2017)

Forecasting Clinical Dose–Response From Preclinical Studies in Tuberculosis Research: Translational Predictions With Rifampicin

Por Wicha, Sebastian G., Clewe, Oskar, Svensson, Robin J., Gillespie, Stephen H., Hu, Yanmin, Coates, Anthony R.M., Simonsson, Ulrika S.H.
Publicado no Clin Pharmacol Ther (2018)

Direct Comparison of Xpert MTB/RIF Assay with Liquid and Solid Mycobacterial Culture for Quantification of Early Bactericidal Activity

Por Kayigire, Xavier A., Friedrich, Sven O., Venter, Amour, Dawson, Rodney, Gillespie, Stephen H., Boeree, Martin J., Heinrich, Norbert, Hoelscher, Michael, Diacon, Andreas H.
Publicado em 2013

Limited role of culture conversion for decision-making in individual patient care and for advancing novel regimens to confirmatory clinical trials

Por Phillips, Patrick P. J., Mendel, Carl M., Burger, Divan A., Crook, Angela, Nunn, Andrew J., Dawson, Rodney, Diacon, Andreas H., Gillespie, Stephen H.
Publicado no BMC Med (2016)