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Microsatellite instability in childhood rhabdomyosarcoma is locus specific and correlates with fractional allelic loss.

Replication errors (RERs) were initially identified in hereditary nonpolyposis colon cancer and other tumors of Lynch syndrome II. Mutations in genes involved in mismatch repair give rise to a mutator phenotype, resulting in RERs. The mutator phenotype is thought to predispose to malignant transform...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Visser, M, Bras, J, Sijmons, C, Devilee, P, Wijnaendts, L C, van der Linden, J C, Voûte, P A, Baas, F
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1996
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38614/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8799173/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.17.9172
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