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Microsatellite instability in childhood rhabdomyosarcoma is locus specific and correlates with fractional allelic loss.

Replication errors (RERs) were initially identified in hereditary nonpolyposis colon cancer and other tumors of Lynch syndrome II. Mutations in genes involved in mismatch repair give rise to a mutator phenotype, resulting in RERs. The mutator phenotype is thought to predispose to malignant transform...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Visser, M, Bras, J, Sijmons, C, Devilee, P, Wijnaendts, L C, van der Linden, J C, Voûte, P A, Baas, F
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38614/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8799173/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.17.9172
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