Microsatellite instability in childhood rhabdomyosarcoma is locus specific and correlates with fractional allelic loss.

Replication errors (RERs) were initially identified in hereditary nonpolyposis colon cancer and other tumors of Lynch syndrome II. Mutations in genes involved in mismatch repair give rise to a mutator phenotype, resulting in RERs. The mutator phenotype is thought to predispose to malignant transform...

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Detalhes bibliográficos
Main Authors: Visser, M, Bras, J, Sijmons, C, Devilee, P, Wijnaendts, L C, van der Linden, J C, Voûte, P A, Baas, F
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC38614/
https://ncbi.nlm.nih.gov/pubmed/8799173
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