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Sphingosine-1-phosphate prevents chemotherapy-induced human primordial follicle death
STUDY QUESTION: Can Sphingosine-1-phosphate (S1P), a ceramide-induced death pathway inhibitor, prevent cyclophosphamide (Cy) or doxorubicin (Doxo) induced apoptotic follicle death in human ovarian xenografts? SUMMARY ANSWER: S1P can block human apoptotic follicle death induced by both drugs, which h...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3860896/ https://ncbi.nlm.nih.gov/pubmed/24221908 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/humrep/det391 |
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