Sphingosine-1-phosphate prevents chemotherapy-induced human primordial follicle death

STUDY QUESTION: Can Sphingosine-1-phosphate (S1P), a ceramide-induced death pathway inhibitor, prevent cyclophosphamide (Cy) or doxorubicin (Doxo) induced apoptotic follicle death in human ovarian xenografts? SUMMARY ANSWER: S1P can block human apoptotic follicle death induced by both drugs, which h...

詳細記述

保存先:
書誌詳細
主要な著者: Li, Fang, Turan, Volkan, Lierman, Sylvie, Cuvelier, Claude, De Sutter, Petra, Oktay, Kutluk
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2014
主題:
Original Articles
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3860896/
https://ncbi.nlm.nih.gov/pubmed/24221908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/humrep/det391
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