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Plasma Biomarkers of Liver Injury and Inflammation Demonstrate a Lack of Apoptosis during Obstructive Cholestasis in Mice

Cholestasis is a pathological common component of numerous liver diseases that results in hepatotoxicity, inflammation, and cirrhosis when untreated. While the predominant hypothesis in cholestatic liver injury remains hepatocyte apoptosis due to direct toxicity of hydrophobic bile acid exposure, re...

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Détails bibliographiques
Auteurs principaux: Woolbright, Benjamin L., Antoine, Daniel J., Jenkins, Rosalind E., Bajt, Mary Lynn, Park, B. Kevin, Jaeschke, Hartmut
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3860754/
https://ncbi.nlm.nih.gov/pubmed/24096036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2013.09.023
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