Cytometric Assessment of DNA Damage by Exogenous and Endogenous Oxidants Reports Aging-related Processes

The ongoing DNA damage caused by reactive oxygen species generated during oxidative metabolism is considered a key factor contributing to cell aging as well as preconditioning cells to neoplastic transformation. We postulated before that a significant fraction of constitutive histone H2AX phosphoryl...

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Bibliographic Details
Main Authors: Zhao, Hong, Tanaka, Toshiki, Halicka, H. Dorota, Traganos, Frank, Zarebski, Miroslaw, Dobrucki, Jurek, Darzynkiewicz, Zbigniew
Format: Artigo
Language:Inglês
Published: 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3860741/
https://ncbi.nlm.nih.gov/pubmed/17879239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cyto.a.20469
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