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A Bayesian Approach to Improved Estimation of Causal Effect Predictiveness for a Principal Surrogate Endpoint

The literature on potential outcomes has shown that traditional methods for characterizing surrogate endpoints in clinical trials based only on observed quantities can fail to capture causal relationships between treatments, surrogates, and outcomes. Building on the potential-outcomes formulation of...

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Detalhes bibliográficos
Main Authors: Zigler, Corwin M., Belin, Thomas R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3860118/
https://ncbi.nlm.nih.gov/pubmed/22348277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1541-0420.2011.01736.x
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