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12/15-Lipoxygenase expression is increased in oligodendrocytes and microglia of periventricular leukomalacia
Oxidative stress involving pre-myelinating oligodendrocytes (OLs) is a major factor in the pathogenesis of preterm white matter injury. In animal and cell culture studies, activation of the lipid-oxidizing enzyme 12/15-lipoxygenase (12/15-LOX) plays a central role as an inflammatory mediator in the...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3860095/ https://ncbi.nlm.nih.gov/pubmed/23838566 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000350230 |
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