High ALK mRNA expression has a negative prognostic significance in rhabdomyosarcoma

BACKGROUND: Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase aberrantly expressed in cancer, but its clinical and functional importance remain controversial. Mutation or amplification of ALK, as well as its expression levels assessed by conventional immunohistochemistry methods, has be...

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Bibliografiske detaljer
Main Authors: Bonvini, P, Zin, A, Alaggio, R, Pawel, B, Bisogno, G, Rosolen, A
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
Fag:
Molecular Diagnostics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859940/
https://ncbi.nlm.nih.gov/pubmed/24149177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.653
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