Galectin-1 has potential prognostic significance and is implicated in clear cell renal cell carcinoma progression through the HIF/mTOR signaling axis

BACKGROUND: Metastatic clear cell renal cell carcinoma (ccRCC) patients have <9% 5-year survival rate, do not respond well to targeted therapy and eventually develop resistance. A better understanding of molecular pathways of RCC metastasis is the basis for the discovery of novel prognostic marke...

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Hlavní autoři: White, N M A, Masui, O, Newsted, D, Scorilas, A, Romaschin, A D, Bjarnason, G A, Siu, K W M, Yousef, G M
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2014
Témata:
Molecular Diagnostics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3950857/
https://ncbi.nlm.nih.gov/pubmed/24496460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.828
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