High ALK mRNA expression has a negative prognostic significance in rhabdomyosarcoma

BACKGROUND: Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase aberrantly expressed in cancer, but its clinical and functional importance remain controversial. Mutation or amplification of ALK, as well as its expression levels assessed by conventional immunohistochemistry methods, has be...

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Detalhes bibliográficos
Main Authors: Bonvini, P, Zin, A, Alaggio, R, Pawel, B, Bisogno, G, Rosolen, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859940/
https://ncbi.nlm.nih.gov/pubmed/24149177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.653
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