An improved whole cell pertussis vaccine with reduced content of endotoxin

An improved whole cell pertussis vaccine, designated as Plow, which is low in endotoxicity due to a chemical extraction of lipo-oligosaccharide (LOS) from the outer membrane, was evaluated for safety, immunogenicity and potency, comparatively to a traditional whole cell pertussis vaccine. Current wh...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Dias, Waldely Oliveira, van der Ark, Arno A.J., Sakauchi, Maria Aparecida, Kubrusly, Flávia Saldanha, Prestes, Ana Fabíola R.O., Borges, Monamaris Marques, Furuyama, Noemi, Horton, Denise S.P.Q., Quintilio, Wagner, Antoniazi, Marta, Kuipers, Betsy, van der Zeijst, Bernard A.M., Raw, Isaias
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Landes Bioscience 2013
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859757/
https://ncbi.nlm.nih.gov/pubmed/23291935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.22847
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