Combination of Pneumococcal Surface Protein A (PspA) with Whole Cell Pertussis Vaccine Increases Protection Against Pneumococcal Challenge in Mice

Streptococcus pneumoniae is the leading cause of respiratory acute infections around the world. In Latin America, approximately 20,000 children under 5 years of age die of pneumococcal diseases annually. Pneumococcal surface protein A (PspA) is among the best-characterized pneumococcal antigens that...

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Detalhes bibliográficos
Main Authors: Oliveira, Maria Leonor S., Miyaji, Eliane N., Ferreira, Daniela M., Moreno, Adriana T., Ferreira, Patricia C. D., Lima, Fernanda A., Santos, Fernanda L., Sakauchi, Maria Aparecida, Takata, Célia S., Higashi, Hisako G., Raw, Isaías, Kubrusly, Flavia S., Ho, Paulo L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877721/
https://ncbi.nlm.nih.gov/pubmed/20523738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010863
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