An improved whole cell pertussis vaccine with reduced content of endotoxin

An improved whole cell pertussis vaccine, designated as Plow, which is low in endotoxicity due to a chemical extraction of lipo-oligosaccharide (LOS) from the outer membrane, was evaluated for safety, immunogenicity and potency, comparatively to a traditional whole cell pertussis vaccine. Current wh...

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Detalhes bibliográficos
Main Authors: Dias, Waldely Oliveira, van der Ark, Arno A.J., Sakauchi, Maria Aparecida, Kubrusly, Flávia Saldanha, Prestes, Ana Fabíola R.O., Borges, Monamaris Marques, Furuyama, Noemi, Horton, Denise S.P.Q., Quintilio, Wagner, Antoniazi, Marta, Kuipers, Betsy, van der Zeijst, Bernard A.M., Raw, Isaias
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859757/
https://ncbi.nlm.nih.gov/pubmed/23291935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.22847
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