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An improved whole cell pertussis vaccine with reduced content of endotoxin
An improved whole cell pertussis vaccine, designated as Plow, which is low in endotoxicity due to a chemical extraction of lipo-oligosaccharide (LOS) from the outer membrane, was evaluated for safety, immunogenicity and potency, comparatively to a traditional whole cell pertussis vaccine. Current wh...
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| Main Authors: | , , , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Landes Bioscience
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3859757/ https://ncbi.nlm.nih.gov/pubmed/23291935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.22847 |
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