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A CpG-containing oligodeoxynucleotide adjuvant for acellular pertussis vaccine improves the protective response against Bordetella pertussis

We investigated the adjuvant effect of CpG ODN alone or in combination with aluminum hydroxide on the immune response to the three main antigens presented in current acellular pertussis vaccines: pertussis toxoid, filamentous haemagglutinin and pertactin. The development of protection in mice was in...

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Bibliografische gegevens
Hoofdauteurs: Asokanathan, Catpagavalli, Corbel, Michael, Xing, Dorothy
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Landes Bioscience 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859755/
https://ncbi.nlm.nih.gov/pubmed/23291942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.22755
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