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A CpG-containing oligodeoxynucleotide adjuvant for acellular pertussis vaccine improves the protective response against Bordetella pertussis

We investigated the adjuvant effect of CpG ODN alone or in combination with aluminum hydroxide on the immune response to the three main antigens presented in current acellular pertussis vaccines: pertussis toxoid, filamentous haemagglutinin and pertactin. The development of protection in mice was in...

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Autori principali: Asokanathan, Catpagavalli, Corbel, Michael, Xing, Dorothy
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859755/
https://ncbi.nlm.nih.gov/pubmed/23291942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.22755
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