Lin28 Induces Epithelial-to-Mesenchymal Transition and Stemness via Downregulation of Let-7a in Breast Cancer Cells

The RNA-binding protein Lin28 is known to promote malignancy by inhibiting the biogenesis of let-7, which functions as a tumor suppressor. However, the role of the Lin28/let-7 axis in the epithelial-to-mesenchymal transition (EMT) and stemness in breast cancer has not been clearly expatiated. In our...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Liu, Yujie, Li, Haiyan, Feng, Juan, Cui, Xiuying, Huang, Wei, Li, Yudong, Su, Fengxi, Liu, Qiang, Zhu, Jiujun, Lv, Xiaobin, Chen, Jianing, Huang, Di, Yu, Fengyan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859647/
https://ncbi.nlm.nih.gov/pubmed/24349438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083083
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi